Discover supporting research and information on how cannabidiol (CBD) relates to the treatment of Inflammation.
Simply put, inflammation is your immune system's response mechanism designed to help protect and repair your body. When suffering from an injury or disease, the body's immune system responds by sending white blood cells to the affected area. These blood cells help repair damaged tissue, stop the spread of infection, or fight off foreign invaders.
Inflammation is often characterized by the production of heat, swelling, and redness at the affected area. Without this important reaction process, your body would be left defenseless. However not all inflammation is good.
When inflammation sticks around longer than it should it can end up harming the body. Chronic inflammation can cause diseases and conditions over a long period of time including cancers, and arthritis.
Acute vs Chronic Inflammation
There are two primary types of inflammation characterized by the duration.
What is Acute Inflammation?
Acute inflammation is a short-term immune response due to an injury or illness. This response often starts aggressively and becomes severe in a short time. The symptoms may only last for a few days up to a few weeks.
Common causes of acute inflammation include:
- Cuts or scrapes
- High-intensity exercise or workouts
- The common cold or flu causing a sore throat
- Acute bronchitis
What is Chronic Inflammation?
Chronic inflammation is a long-term inflammatory response that often comes on slowly and lasts from several months to years. Although inflammation's role in repairing the body is critical, chronic inflammation can eventually cause tissue death and scarring of connective tissue resulting in disease. Because of these risks, this long-lasting condition needs to be successfully managed to prevent damage or disease to the body.
Common conditions and diseases that include chronic inflammation include:
- Rheumatoid arthritis
- Chronic peptic ulcer
Chronic inflammation can be caused by:
- Failure to heal or eliminate the cause of an acute inflammatory response
- An autoimmune disorder that mistakenly attacks healthy tissue in the body
- Long-term exposure to an irritant that causes inflammation such as a harmful chemical
Inflammation and Pain
Pain an inflammation often go hand-in-hand. Depending on the severity, pain, stiffness, and discomfort of varying levels is often accompanied with inflammation.
This pain is primarily caused due to the fact that the swelling pushes against nerve endings, sending pain signals to the brain. Due to the nature of inflammation, these pain sensations can range from throbbing to steady, to stabbing, to pinching.
Treating Inflammation with CBD
Among the various conditions that cannabis is being shown to effectively treat, inflammation is one of the most well documented due to its occurrence in so many conditions. Research has shown that CBD suppresses the inflammatory response and attenuate disease symptoms. Beyond CBD, studies show that other cannabinoids provide increased anti-inflammatory benefits. These cannabinoids include CBG, THC, and unheated acid forms including THCA and CBDA.
This points to cannabis' potential as an effective medicine to fight a wide range of issues from chronic pain to arthritis to multiple sclerosis to cancer. These same effects are widely supported by anecdotal evidence. There are a wide number of products being used daily to treat inflammation in people of all walks of life.
Standard dosages apply - commonly 10-25mg per day for capsules or tinctures. Topicals use as directed.
For more information, see our dosage guidelines for CBD.
- Cannabidiolic acid as a selective cyclooxygenase-2 inhibitory component in cannabis. (September 2008) – https://www.ncbi.nlm.nih.gov/pubmed/18556441
- Cannabinoids, endocannabinoids, and related analogs in inflammation. (March 2009) – https://www.ncbi.nlm.nih.gov/pubmed/19199042
- Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation. (March 2010) – https://www.ncbi.nlm.nih.gov/pubmed/21537423
- Cannabinoids as novel anti-inflammatory drugs (August 2010) – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/
- Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis. (2011) – https://www.ncbi.nlm.nih.gov/pubmed/22163000
- Cannabidiol reduces Aβ-induced neuroinflammation and promotes hippocampal neurogenesis through PPARγ involvement. (2011) – https://www.ncbi.nlm.nih.gov/pubmed/22163051
- Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors. (June 2012) – https://www.ncbi.nlm.nih.gov/pubmed/22585736
- Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice. (June 2012) – https://www.ncbi.nlm.nih.gov/pubmed/22300105
- Cannabinoids, inflammation, and fibrosis. (November 2016) – https://www.ncbi.nlm.nih.gov/pubmed/27435265
- The Cannabinoids Δ8THC, CBD, and HU-308 Act via Distinct Receptors to Reduce Corneal Pain and Inflammation. (February 2018) – https://www.ncbi.nlm.nih.gov/pubmed/29450258
- Anti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact Dermatitis. (June 2018) – https://www.ncbi.nlm.nih.gov/pubmed/29632236
The contents of this page are not medical advice. Please seek professional medical assistance for any condition and before starting, stoping, or changing medication or supplements.